[Design, synthesis and evaluation of tacrine-methoxybenzene hybrids as cholinesterases inhibitors].

Luo, Wen; Zhao, Yong-Mei; Zhang, Zhen; Su, Ya-Bin; Wang, Chao-Jie

Luo, Wen; Zhao, Yong-Mei; Zhang, Zhen; Su, Ya-Bin; Wang, Chao-Jie.

Affiliation

Luo W; Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng 475004, China. luowen83@henu.edu.cn

Yao Xue Xue Bao ; 47(7): 916-21, 2012 Jul.

Article in Zh | MEDLINE | ID: mdl-22993857

Subject(s)

Acetylcholinesterase/metabolism; Anisoles/chemical synthesis; Butyrylcholinesterase/metabolism; Cholinesterase Inhibitors/chemical synthesis; Tacrine/chemical synthesis; Anisoles/chemistry; Anisoles/pharmacology; Binding Sites; Catalytic Domain; Cholinesterase Inhibitors/chemistry; Cholinesterase Inhibitors/pharmacology; Drug Design; Inhibitory Concentration 50; Tacrine/chemistry; Tacrine/pharmacology

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PubMed Links

Database: MEDLINE Main subject: Acetylcholinesterase / Tacrine / Butyrylcholinesterase / Cholinesterase Inhibitors / Anisoles Language: Zh Year: 2012 Type: Article

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PubMed Links

Database: MEDLINE Main subject: Acetylcholinesterase / Tacrine / Butyrylcholinesterase / Cholinesterase Inhibitors / Anisoles Language: Zh Year: 2012 Type: Article