Refractory neuro-Behçet treated by tocilizumab: a case report.
Clin Exp Rheumatol
; 30(3 Suppl 72): S73-5, 2012.
Article
in En
| MEDLINE
| ID: mdl-23020826
ABSTRACT
A patient with central nervous system involvement of Behçet's disease was refractory to conventional immunosuppressive therapy and showed secondary failure of the anti-TNF agent infliximab. This presented as a progressive weakness of the legs and reduction in walking distance. The cerebrospinal fluid showed signs of inflammation including a vastly elevated IL-6 concentration. Given this result, the anti-IL-6 receptor antibody tocilizumab was administered and a good improvement of inflammatory parameters and a satisfactory increase of the walking distance were achieved.
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Database:
MEDLINE
Main subject:
Central Nervous System Diseases
/
Behcet Syndrome
/
Lower Extremity
/
Antibodies, Monoclonal, Humanized
/
Immunosuppressive Agents
Type of study:
Diagnostic_studies
/
Etiology_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Year:
2012
Type:
Article