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A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance.
Vandenbark, Arthur A; Meza-Romero, Roberto; Benedek, Gil; Andrew, Shayne; Huan, Jianya; Chou, Yuan K; Buenafe, Abigail C; Dahan, Rony; Reiter, Yoram; Mooney, Jeffery L; Offner, Halina; Burrows, Gregory G.
Affiliation
  • Vandenbark AA; Research Service, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
  • Meza-Romero R; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
  • Benedek G; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.
  • Andrew S; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
  • Huan J; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR 97239, USA.
  • Chou YK; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
  • Buenafe AC; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.
  • Dahan R; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
  • Reiter Y; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.
  • Mooney JL; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.
  • Offner H; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.
  • Burrows GG; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.
J Autoimmun ; 40: 96-110, 2013 Feb.
Article in En | MEDLINE | ID: mdl-23026773

Full text: 1 Database: MEDLINE Main subject: Autoimmune Diseases / Monocytes / Antigens, Differentiation, B-Lymphocyte / Histocompatibility Antigens Class II Limits: Animals Language: En Year: 2013 Type: Article

Full text: 1 Database: MEDLINE Main subject: Autoimmune Diseases / Monocytes / Antigens, Differentiation, B-Lymphocyte / Histocompatibility Antigens Class II Limits: Animals Language: En Year: 2013 Type: Article