Glucocorticoid suppresses dendritic spine development mediated by down-regulation of caldesmon expression.

Tanokashira, Daisuke; Morita, Tsuyoshi; Hayashi, Ken'ichiro; Mayanagi, Taira; Fukumoto, Kentaro; Kubota, Yoshiko; Yamashita, Toshihide; Sobue, Kenji

Tanokashira, Daisuke; Morita, Tsuyoshi; Hayashi, Ken'ichiro; Mayanagi, Taira; Fukumoto, Kentaro; Kubota, Yoshiko; Yamashita, Toshihide; Sobue, Kenji.

Affiliation

Tanokashira D; Department of Neuroscience, Graduate School of Medicine, Osaka University, Suita, Osaka 565-0871, Japan.

J Neurosci ; 32(42): 14583-91, 2012 Oct 17.

Article in En | MEDLINE | ID: mdl-23077044

Subject(s)

Calmodulin-Binding Proteins/antagonists & inhibitors; Calmodulin-Binding Proteins/biosynthesis; Corticosterone/pharmacology; Dendritic Spines/physiology; Down-Regulation/genetics; Gene Expression Regulation, Developmental/physiology; Neurogenesis/genetics; Actins/antagonists & inhibitors; Actins/metabolism; Animals; Calmodulin-Binding Proteins/genetics; Cells, Cultured; Dendritic Spines/drug effects; Down-Regulation/drug effects; Humans; Male; Neurogenesis/drug effects; Protein Binding/drug effects; Protein Binding/genetics; Random Allocation; Rats; Rats, Wistar

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Full text: 1 Database: MEDLINE Main subject: Calmodulin-Binding Proteins / Corticosterone / Down-Regulation / Gene Expression Regulation, Developmental / Dendritic Spines / Neurogenesis Type of study: Clinical_trials Limits: Animals / Humans / Male Language: En Year: 2012 Type: Article

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