Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase.

Aslam, Muhammad; Schluter, Klaus-Dieter; Rohrbach, Susanne; Rafiq, Amir; Nazli, Sabiha; Piper, Hans Michael; Noll, Thomas; Schulz, Rainer; Gündüz, Dursun

Aslam, Muhammad; Schluter, Klaus-Dieter; Rohrbach, Susanne; Rafiq, Amir; Nazli, Sabiha; Piper, Hans Michael; Noll, Thomas; Schulz, Rainer; Gündüz, Dursun.

Affiliation

Aslam M; Physiologisches Institut, Justus-Liebig-Universität, Giessen, Germany. muhammad.aslam@physiologie.med.uni-giessen.de

J Physiol ; 591(2): 461-73, 2013 Jan 15.

Article in En | MEDLINE | ID: mdl-23090948

Subject(s)

Endothelial Cells/metabolism; Muscle, Smooth, Vascular/physiology; Myosin-Light-Chain Kinase/metabolism; rac1 GTP-Binding Protein/metabolism; rhoA GTP-Binding Protein/metabolism; Actins/metabolism; Adherens Junctions/metabolism; Animals; Antigens, CD/metabolism; Aorta/cytology; Aorta/physiology; Cadherins/metabolism; Calcium/metabolism; Cell Hypoxia; Cyclic AMP/analogs & derivatives; Cyclic AMP/pharmacology; Guanine Nucleotide Exchange Factors/antagonists & inhibitors; Guanine Nucleotide Exchange Factors/metabolism; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Permeability; Rats; Signal Transduction; Stress Fibers/metabolism; Swine; Vasoconstriction; rho-Associated Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Myosin-Light-Chain Kinase / Rac1 GTP-Binding Protein / RhoA GTP-Binding Protein / Endothelial Cells / Muscle, Smooth, Vascular Limits: Animals / Humans Language: En Year: 2013 Type: Article

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