Cripto regulates skeletal muscle regeneration and modulates satellite cell determination by antagonizing myostatin.

Guardiola, Ombretta; Lafuste, Peggy; Brunelli, Silvia; Iaconis, Salvatore; Touvier, Thierry; Mourikis, Philippos; De Bock, Katrien; Lonardo, Enza; Andolfi, Gennaro; Bouché, Ann; Liguori, Giovanna L; Shen, Michael M; Tajbakhsh, Shahragim; Cossu, Giulio; Carmeliet, Peter; Minchiotti, Gabriella

Guardiola, Ombretta; Lafuste, Peggy; Brunelli, Silvia; Iaconis, Salvatore; Touvier, Thierry; Mourikis, Philippos; De Bock, Katrien; Lonardo, Enza; Andolfi, Gennaro; Bouché, Ann; Liguori, Giovanna L; Shen, Michael M; Tajbakhsh, Shahragim; Cossu, Giulio; Carmeliet, Peter; Minchiotti, Gabriella.

Affiliation

Guardiola O; Stem Cell Fate Laboratory, Institute of Genetics and Biophysics "Adriano Buzzati-Traverso," Consiglio Nazionale delle Ricerche, 80131 Naples, Italy.

Proc Natl Acad Sci U S A ; 109(47): E3231-40, 2012 Nov 20.

Article in En | MEDLINE | ID: mdl-23129614

Subject(s)

Cell Lineage; Epidermal Growth Factor/metabolism; Membrane Glycoproteins/metabolism; Muscle, Skeletal/physiology; Myostatin/antagonists & inhibitors; Neoplasm Proteins/metabolism; Regeneration; Satellite Cells, Skeletal Muscle/metabolism; Satellite Cells, Skeletal Muscle/pathology; Aging/metabolism; Animals; Cell Proliferation; Gene Deletion; Gene Targeting; Hypertrophy; Mice; Mice, Inbred C57BL; Models, Animal; Muscle Development; Muscle Fibers, Skeletal/metabolism; Muscle Fibers, Skeletal/pathology; Muscle, Skeletal/metabolism; Muscle, Skeletal/pathology; Myoblasts/metabolism; Myoblasts/pathology; Myostatin/metabolism; Signal Transduction

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Full text: 1 Database: MEDLINE Main subject: Regeneration / Membrane Glycoproteins / Muscle, Skeletal / Cell Lineage / Satellite Cells, Skeletal Muscle / Epidermal Growth Factor / Myostatin / Neoplasm Proteins Type of study: Prognostic_studies Limits: Animals Language: En Year: 2012 Type: Article

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