Activation of liver X receptor induces macrophage interleukin-5 expression.

Chen, Yuanli; Duan, Yajun; Kang, Yanhua; Yang, Xiaoxiao; Jiang, Meixiu; Zhang, Ling; Li, Guangliang; Yin, Zhinan; Hu, Wenquan; Dong, Pengzhi; Li, Xiaoju; Hajjar, David P; Han, Jihong

Chen, Yuanli; Duan, Yajun; Kang, Yanhua; Yang, Xiaoxiao; Jiang, Meixiu; Zhang, Ling; Li, Guangliang; Yin, Zhinan; Hu, Wenquan; Dong, Pengzhi; Li, Xiaoju; Hajjar, David P; Han, Jihong.

Affiliation

Chen Y; State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.

J Biol Chem ; 287(52): 43340-50, 2012 Dec 21.

Article in En | MEDLINE | ID: mdl-23150660

Subject(s)

Cholesterol/metabolism; Gene Expression Regulation; Interleukin-5/biosynthesis; Macrophages/metabolism; Orphan Nuclear Receptors/metabolism; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters/biosynthesis; ATP-Binding Cassette Transporters/genetics; Animals; Aorta/metabolism; Atherosclerosis/genetics; Atherosclerosis/metabolism; Cell Line; Cholesterol/genetics; Gene Knockdown Techniques; Hydrocarbons, Fluorinated/pharmacology; Immunoglobulin M/biosynthesis; Immunoglobulin M/genetics; Interleukin-5/genetics; Liver X Receptors; Macrophages/pathology; Mice; Mice, Knockout; Orphan Nuclear Receptors/agonists; Orphan Nuclear Receptors/genetics; Response Elements/genetics; Sulfonamides/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation / Cholesterol / Interleukin-5 / Orphan Nuclear Receptors / Macrophages Limits: Animals Language: En Year: 2012 Type: Article

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