Interleukin-33 drives a proinflammatory endothelial activation that selectively targets nonquiescent cells.

Pollheimer, Jürgen; Bodin, Johanna; Sundnes, Olav; Edelmann, Reidunn J; Skånland, Sigrid S; Sponheim, Jon; Brox, Mari Johanna; Sundlisaeter, Eirik; Loos, Tamara; Vatn, Morten; Kasprzycka, Monika; Wang, Junbai; Küchler, Axel M; Taskén, Kjetil; Haraldsen, Guttorm; Hol, Johanna

Pollheimer, Jürgen; Bodin, Johanna; Sundnes, Olav; Edelmann, Reidunn J; Skånland, Sigrid S; Sponheim, Jon; Brox, Mari Johanna; Sundlisaeter, Eirik; Loos, Tamara; Vatn, Morten; Kasprzycka, Monika; Wang, Junbai; Küchler, Axel M; Taskén, Kjetil; Haraldsen, Guttorm; Hol, Johanna.

Affiliation

Pollheimer J; LIIPAT, Institute of Pathology, University of Oslo, Oslo, Norway.

Arterioscler Thromb Vasc Biol ; 33(2): e47-55, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23162017

Subject(s)

Cell Proliferation; Dermatitis/immunology; Endothelial Cells/immunology; Inflammation Mediators/metabolism; Interleukins/metabolism; Skin/blood supply; Adenoviridae/genetics; Animals; Biopsy; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p27/metabolism; Dermatitis/pathology; E-Selectin/metabolism; Endothelial Cells/pathology; Female; Flow Cytometry; Genetic Vectors; Human Umbilical Vein Endothelial Cells/immunology; Humans; Interleukin-1beta/metabolism; Interleukin-33; Interleukins/genetics; JNK Mitogen-Activated Protein Kinases/metabolism; Mice; Mice, Inbred C57BL; NF-kappa B/metabolism; Neovascularization, Physiologic; Phosphorylation; RNA Interference; Receptors, Interleukin/metabolism; Retinoblastoma Protein/metabolism; Signal Transduction; Transcription, Genetic; Transduction, Genetic; Transfection; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Skin / Interleukins / Inflammation Mediators / Endothelial Cells / Cell Proliferation / Dermatitis Language: En Year: 2013 Type: Article

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