Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels.

Sun, Yuyang; Selvaraj, Senthil; Varma, Archana; Derry, Susan; Sahmoun, Abe E; Singh, Brij B

Sun, Yuyang; Selvaraj, Senthil; Varma, Archana; Derry, Susan; Sahmoun, Abe E; Singh, Brij B.

Affiliation

Sun Y; Department of Biochemistry and Molecular Biology, University of North Dakota, Grand Forks, North Dakota 58201, USA.

J Biol Chem ; 288(1): 255-63, 2013 Jan 04.

Article in En | MEDLINE | ID: mdl-23168410

Subject(s)

Calcium/chemistry; Gene Expression Regulation, Neoplastic; Magnesium/chemistry; Prostatic Neoplasms/metabolism; TRPM Cation Channels/metabolism; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Cell Survival; Electrophysiology/methods; Humans; Ions; Male; Microscopy, Confocal/methods; Patch-Clamp Techniques; Protein Serine-Threonine Kinases

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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / Gene Expression Regulation, Neoplastic / Calcium / TRPM Cation Channels / Magnesium Type of study: Prognostic_studies Limits: Humans / Male Language: En Year: 2013 Type: Article

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