Incidence of second hip fracture and compliant use of bisphosphonate.
Osteoporos Int
; 24(7): 2099-104, 2013 Jul.
Article
in En
| MEDLINE
| ID: mdl-23247329
ABSTRACT
UNLABELLED We determined the incidence of second hip fracture and evaluated whether compliant users of bisphosphonate had a lower incidence of second hip fracture after prior hip fracture. INTRODUCTION:
Bisphosphonate has been used to prevent osteoporotic fracture and is recommended for the secondary prevention after hip fracture. However, little is known regarding secondary prevention after first hip fracture. Our purpose was to determine the incidence of second hip fracture and to evaluate whether compliant use of bisphosphonate can reduce the risk of second hip fracture.METHODS:
Eight hundred twenty-six patients who sustained the first hip fracture from May 2003 to October 2011 were retrospectively evaluated. The incidence of second hip fracture was compared between compliant users of bisphosphonate and nonusers.RESULTS:
Seventy-one (8.6 %) patients suffered a second hip fracture at mean 30.0 months (SD 24.6, range 1 to 90 months) after the initial hip fracture. The cumulative incidence of second hip fracture was 5.1 % (42/826) at 2 years and 8.6 % (71/826) at 8 years. The incidence of second hip fracture was 4.2 % (12/283) in compliant users and 10.9 % (59/543) in nonusers (p = 0.001).CONCLUSIONS:
Compliant use of bisphosphonate is effective in the prevention of second hip fractures.
Full text:
1
Database:
MEDLINE
Main subject:
Diphosphonates
/
Bone Density Conservation Agents
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Medication Adherence
/
Osteoporotic Fractures
/
Hip Fractures
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Year:
2013
Type:
Article