Apoptosis; Glycation End Products, Advanced/metabolism; Islets of Langerhans/pathology; NADPH Oxidases/metabolism; Reactive Oxygen Species/metabolism; Superoxides/metabolism; Albumins/metabolism; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Glucose/metabolism; Glycation End Products, Advanced/genetics; Islets of Langerhans/metabolism; Luminescence; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; NF-kappa B p50 Subunit/genetics; NF-kappa B p50 Subunit/metabolism; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; RNA, Messenger/genetics; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor for Advanced Glycation End Products; Receptors, Immunologic/genetics; Receptors, Immunologic/metabolism; Reverse Transcriptase Polymerase Chain Reaction; bcl-2-Associated X Protein/genetics; bcl-2-Associated X Protein/metabolism