Identification of active Plasmodium falciparum calpain to establish screening system for Pf-calpain-based drug development.

Soh, Byoung Yul; Song, Hyun-Ok; Lee, Yoonji; Lee, Junghyun; Kaewintajuk, Kusuma; Lee, Binna; Choi, Yun-Young; Cho, Jeong Hoon; Choi, Sun; Park, Hyun

Soh, Byoung Yul; Song, Hyun-Ok; Lee, Yoonji; Lee, Junghyun; Kaewintajuk, Kusuma; Lee, Binna; Choi, Yun-Young; Cho, Jeong Hoon; Choi, Sun; Park, Hyun.

Affiliation

Soh BY; Laboratory of Cell & Molecular Biology, Department of Life Science, Seonam University, Namwon, Jeonbuk 590-711, Republic of Korea.

Malar J ; 12: 47, 2013 Feb 04.

Article in En | MEDLINE | ID: mdl-23374507

Subject(s)

Antimalarials/pharmacology; Calpain/antagonists & inhibitors; Drug Evaluation, Preclinical/methods; High-Throughput Screening Assays/methods; Plasmodium falciparum/drug effects; Plasmodium falciparum/enzymology; Amino Acid Sequence; Antimalarials/isolation & purification; Calpain/genetics; Calpain/isolation & purification; Models, Molecular; Molecular Sequence Data; Protein Conformation; Recombinant Proteins/antagonists & inhibitors; Recombinant Proteins/genetics; Recombinant Proteins/isolation & purification; Sequence Homology, Amino Acid

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Full text: 1 Database: MEDLINE Main subject: Plasmodium falciparum / Calpain / Drug Evaluation, Preclinical / High-Throughput Screening Assays / Antimalarials Type of study: Diagnostic_studies / Prognostic_studies / Screening_studies Language: En Year: 2013 Type: Article

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