Pediatric anophthalmic sockets and orbital implants: outcomes with polymer-coated implants.
Ophthalmology
; 120(6): 1300-4, 2013 Jun.
Article
in En
| MEDLINE
| ID: mdl-23399376
ABSTRACT
PURPOSE:
To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies.DESIGN:
Retrospective, interventional cohort study.PARTICIPANTS:
All children undergoing primary enucleation without adjuvant therapies between 1999 and 2009 at a tertiary pediatric cancer hospital.METHODS:
Review and analysis of patient records. MAIN OUTCOMEMEASURES:
Implant exposure, extrusion and migration, socket contracture, and formation of pyogenic granuloma.RESULTS:
Sixty consecutive patients undergoing primary enucleation with no adjuvant chemotherapy or radiation with follow-up of at least 12 months were included. Retinoblastoma was the diagnosis in 59 eyes (98.3%). Median follow-up was 3.6 years (range, 1.0-9.3 years). Two implant sizes were used 20 mm in 47 patients (78.3%) and 18 mm in 13 patients (21.7%). Overall, 52 patients (86.7%) had an event-free recovery. Polymer-coated hydroxyapatite implants (43/60, 71.7%), when compared with wrapped ones (17/60, 28.3%), had a trend toward greater event-free recovery (odds ratio [OR], 1.6; 95% confidence interval [CI], 0.3-7.7) and lower exposure rate (OR, 2.1; 95% CI, 0.4-10.5).CONCLUSIONS:
The use of polymer-coated hydroxyapatite implants is associated with favorable outcomes in the pediatric population. Despite observed complications, long-term implant retention is possible in most children. FINANCIAL DISCLOSURE(S) The author(s) have no proprietary or commercial interest in any materials discussed in this article.
Full text:
1
Database:
MEDLINE
Main subject:
Orbit
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Polyglactin 910
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Eye Enucleation
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Anophthalmos
/
Durapatite
/
Coated Materials, Biocompatible
/
Orbital Implants
/
Acellular Dermis
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Male
Language:
En
Year:
2013
Type:
Article