Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms.

Malhotra, Ankit; Lindberg, Michael; Faust, Gregory G; Leibowitz, Mitchell L; Clark, Royden A; Layer, Ryan M; Quinlan, Aaron R; Hall, Ira M

Malhotra, Ankit; Lindberg, Michael; Faust, Gregory G; Leibowitz, Mitchell L; Clark, Royden A; Layer, Ryan M; Quinlan, Aaron R; Hall, Ira M.

Affiliation

Malhotra A; Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia 22903, USA.

Genome Res ; 23(5): 762-76, 2013 May.

Article in En | MEDLINE | ID: mdl-23410887

Subject(s)

Chromosome Aberrations; Chromosome Breakpoints; Mutation/genetics; Neoplasms/genetics; Base Sequence; DNA Breaks, Double-Stranded; DNA Replication/genetics; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Neoplasms/pathology

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Full text: 1 Database: MEDLINE Main subject: Chromosome Aberrations / Chromosome Breakpoints / Mutation / Neoplasms Type of study: Risk_factors_studies Limits: Humans Language: En Year: 2013 Type: Article

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