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Endocytosis regulates VEGF signalling during angiogenesis.
Gaengel, Konstantin; Betsholtz, Christer.
Affiliation
  • Gaengel K; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.
Nat Cell Biol ; 15(3): 233-5, 2013 Mar.
Article in En | MEDLINE | ID: mdl-23449144
ABSTRACT
Endocytosis has proved to be a versatile mechanism regulating diverse cellular processes, ranging from nutrient uptake to intracellular signal transduction. New work reinforces the importance of endocytosis for VEGF receptor signalling and angiogenesis in the developing eye, and describes a mechanism for its differential regulation in angiogenic versus quiescent endothelial cells.
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Full text: 1 Database: MEDLINE Main subject: Protein Kinase C / Endothelium, Vascular / Cell Adhesion Molecules / Neovascularization, Physiologic / Receptors, Vascular Endothelial Growth Factor / Ephrin-B2 / Adaptor Proteins, Vesicular Transport / Endocytosis Limits: Animals / Female / Humans / Male Language: En Year: 2013 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Protein Kinase C / Endothelium, Vascular / Cell Adhesion Molecules / Neovascularization, Physiologic / Receptors, Vascular Endothelial Growth Factor / Ephrin-B2 / Adaptor Proteins, Vesicular Transport / Endocytosis Limits: Animals / Female / Humans / Male Language: En Year: 2013 Type: Article