A phase II single-arm study of irinotecan in combination with temozolomide (TEMIRI) in children with newly diagnosed high grade glioma: a joint ITCC and SIOPE-brain tumour study.

Hargrave, Darren; Geoerger, Birgit; Frappaz, Didier; Pietsch, Torsten; Gesner, Lyle; Cisar, Laura; Breazna, Aurora; Dorman, Andrew; Cruz-Martinez, Ofelia; Fuster, Jose Luis; Rialland, Xavier; Icher, Céline; Leblond, Pierre; Ashley, David; Perilongo, Giorgio; Elliott, Martin; English, Martin; Clausen, Niels; Grill, Jacques

Hargrave, Darren; Geoerger, Birgit; Frappaz, Didier; Pietsch, Torsten; Gesner, Lyle; Cisar, Laura; Breazna, Aurora; Dorman, Andrew; Cruz-Martinez, Ofelia; Fuster, Jose Luis; Rialland, Xavier; Icher, Céline; Leblond, Pierre; Ashley, David; Perilongo, Giorgio; Elliott, Martin; English, Martin; Clausen, Niels; Grill, Jacques.

Affiliation

Hargrave D; Paediatric Oncology Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. darren.hargrave@nhs.net

J Neurooncol ; 113(1): 127-34, 2013 May.

Article in En | MEDLINE | ID: mdl-23459995

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/therapeutic use; Brain Neoplasms/drug therapy; Glioma/drug therapy; Adolescent; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Brain Neoplasms/pathology; Camptothecin/administration & dosage; Camptothecin/adverse effects; Camptothecin/analogs & derivatives; Child; Child, Preschool; Dacarbazine/administration & dosage; Dacarbazine/adverse effects; Dacarbazine/analogs & derivatives; Female; Glioma/pathology; Humans; Irinotecan; Male; Neoplasm Grading; Temozolomide; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Brain Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Glioma Type of study: Clinical_trials / Diagnostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Male Language: En Year: 2013 Type: Article

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