µ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche.

Contet, Candice; Kim, Airee; Le, David; Iyengar, Siddharth K; Kotzebue, Roxanne W; Yuan, Clara J; Kieffer, Brigitte L; Mandyam, Chitra D

Contet, Candice; Kim, Airee; Le, David; Iyengar, Siddharth K; Kotzebue, Roxanne W; Yuan, Clara J; Kieffer, Brigitte L; Mandyam, Chitra D.

Affiliation

Contet C; Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA, USA.

Addict Biol ; 19(5): 770-80, 2014 Sep.

Article in En | MEDLINE | ID: mdl-23461397

Subject(s)

Binge Drinking/physiopathology; Hippocampus/drug effects; Receptors, Opioid, mu/physiology; Analysis of Variance; Animals; Antimetabolites/pharmacology; Bromodeoxyuridine/pharmacology; Cell Differentiation/drug effects; Cell Proliferation/drug effects; Doublecortin Protein; Hippocampus/cytology; Male; Mice, Inbred C57BL; Mice, Knockout; Neuroimmunomodulation/drug effects; Neurons/drug effects; Neurons/metabolism; Receptors, Opioid, mu/deficiency; Self Administration; Signal Transduction/drug effects

Key words

AC3; BrdU; DCX; Iba1; Ki-67; neurogenesis

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Full text: 1 Database: MEDLINE Main subject: Receptors, Opioid, mu / Binge Drinking / Hippocampus Limits: Animals Language: En Year: 2014 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Receptors, Opioid, mu / Binge Drinking / Hippocampus Limits: Animals Language: En Year: 2014 Type: Article