Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling.

Weber, Michaela; Gawanbacht, Ali; Habjan, Matthias; Rang, Andreas; Borner, Christoph; Schmidt, Anna Mareike; Veitinger, Sophie; Jacob, Ralf; Devignot, Stéphanie; Kochs, Georg; García-Sastre, Adolfo; Weber, Friedemann

Weber, Michaela; Gawanbacht, Ali; Habjan, Matthias; Rang, Andreas; Borner, Christoph; Schmidt, Anna Mareike; Veitinger, Sophie; Jacob, Ralf; Devignot, Stéphanie; Kochs, Georg; García-Sastre, Adolfo; Weber, Friedemann.

Affiliation

Weber M; Institute for Virology, Philipps-University Marburg, 35043 Marburg, Germany.

Cell Host Microbe ; 13(3): 336-46, 2013 Mar 13.

Article in En | MEDLINE | ID: mdl-23498958

Subject(s)

DEAD-box RNA Helicases/immunology; Nucleocapsid/immunology; RNA Virus Infections/enzymology; RNA Virus Infections/immunology; RNA Viruses/immunology; Adaptor Proteins, Signal Transducing/genetics; Adaptor Proteins, Signal Transducing/immunology; DEAD Box Protein 58; DEAD-box RNA Helicases/chemistry; DEAD-box RNA Helicases/genetics; Genome, Viral; Host-Pathogen Interactions; Humans; Nucleocapsid/chemistry; Nucleocapsid/genetics; Polyphosphates/metabolism; RNA Virus Infections/genetics; RNA Virus Infections/virology; RNA Viruses/chemistry; RNA Viruses/genetics; RNA, Viral/chemistry; RNA, Viral/genetics; RNA, Viral/immunology; Receptors, Immunologic; Signal Transduction

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Full text: 1 Database: MEDLINE Main subject: RNA Virus Infections / RNA Viruses / Nucleocapsid / DEAD-box RNA Helicases Limits: Humans Language: En Year: 2013 Type: Article

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