Sunitinib in combination with gemcitabine for advanced solid tumours: a phase I dose-finding study.

Michaelson, M D; Zhu, A X; Ryan, D P; McDermott, D F; Shapiro, G I; Tye, L; Chen, I; Stephenson, P; Patyna, S; Ruiz-Garcia, A; Schwarzberg, A B

Michaelson, M D; Zhu, A X; Ryan, D P; McDermott, D F; Shapiro, G I; Tye, L; Chen, I; Stephenson, P; Patyna, S; Ruiz-Garcia, A; Schwarzberg, A B.

Affiliation

Michaelson MD; Massachusetts General Hospital Cancer Center, 55 Fruit Street, Yawkey 7, Boston, MA 02114, USA. dmichaelson1@partners.org

Br J Cancer ; 108(7): 1393-401, 2013 Apr 16.

Article in En | MEDLINE | ID: mdl-23511559

Subject(s)

Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/adverse effects; Neoplasms/drug therapy; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols/pharmacokinetics; Deoxycytidine/administration & dosage; Deoxycytidine/adverse effects; Deoxycytidine/analogs & derivatives; Deoxycytidine/pharmacokinetics; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Indoles/administration & dosage; Indoles/adverse effects; Indoles/pharmacokinetics; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms/metabolism; Neoplasms/pathology; Pyrroles/administration & dosage; Pyrroles/adverse effects; Pyrroles/pharmacokinetics; Sunitinib; Gemcitabine

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Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Neoplasms Type of study: Clinical_trials / Diagnostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Year: 2013 Type: Article

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