Influence of the surface coating on the cytotoxicity, genotoxicity and uptake of gold nanoparticles in human HepG2 cells.

Fraga, Sónia; Faria, Helena; Soares, Maria Elisa; Duarte, José Alberto; Soares, Leonor; Pereira, Eulália; Costa-Pereira, Cristiana; Teixeira, João Paulo; de Lourdes Bastos, Maria; Carmo, Helena

Fraga, Sónia; Faria, Helena; Soares, Maria Elisa; Duarte, José Alberto; Soares, Leonor; Pereira, Eulália; Costa-Pereira, Cristiana; Teixeira, João Paulo; de Lourdes Bastos, Maria; Carmo, Helena.

Affiliation

Fraga S; REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313, Porto, Portugal. teixeirafraga@hotmail.com

J Appl Toxicol ; 33(10): 1111-9, 2013 Oct.

Article in En | MEDLINE | ID: mdl-23529830

Subject(s)

Coated Materials, Biocompatible/toxicity; DNA Damage/drug effects; Gold/toxicity; Metal Nanoparticles/toxicity; Cell Survival/drug effects; Citric Acid/chemistry; Coated Materials, Biocompatible/chemistry; Comet Assay; Fatty Acids/chemistry; Genomic Instability; Gold/chemistry; Hep G2 Cells; Humans; Metal Nanoparticles/chemistry; Microscopy, Electron, Transmission; Particle Size; Sulfhydryl Compounds/chemistry; Surface Properties; Tetrazolium Salts/metabolism; Thiazoles/metabolism

Key words

DNA damage; HepG2 cells; cellular uptake; cytotoxicity; gold nanoparticles; surface properties

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: DNA Damage / Coated Materials, Biocompatible / Metal Nanoparticles / Gold Limits: Humans Language: En Year: 2013 Type: Article

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: DNA Damage / Coated Materials, Biocompatible / Metal Nanoparticles / Gold Limits: Humans Language: En Year: 2013 Type: Article