Methotrexate/iatrogenic lymphoproliferative disorders in rheumatoid arthritis: histology, Epstein-Barr virus, and clonality are important predictors of disease progression and regression.

Ichikawa, Ayako; Arakawa, Fumiko; Kiyasu, Junichi; Sato, Kensaku; Miyoshi, Hiroaki; Niino, Daisuke; Kimura, Yoshizo; Takeuchi, Masanori; Yoshida, Maki; Ishibashi, Yukinao; Nakashima, Shinji; Sugita, Yasuo; Miura, Osamu; Ohshima, Koichi

Ichikawa, Ayako; Arakawa, Fumiko; Kiyasu, Junichi; Sato, Kensaku; Miyoshi, Hiroaki; Niino, Daisuke; Kimura, Yoshizo; Takeuchi, Masanori; Yoshida, Maki; Ishibashi, Yukinao; Nakashima, Shinji; Sugita, Yasuo; Miura, Osamu; Ohshima, Koichi.

Affiliation

Ichikawa A; Department of Pathology, School of Medicine, Kurume University, Kurume, Japan. rikoayako@hotmail.co.jp

Eur J Haematol ; 91(1): 20-8, 2013 Jul.

Article in En | MEDLINE | ID: mdl-23560463

Subject(s)

Arthritis, Rheumatoid/drug therapy; Herpesvirus 4, Human/isolation & purification; Lymphoproliferative Disorders/chemically induced; Methotrexate/therapeutic use; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic/therapeutic use; Arthritis, Rheumatoid/complications; Arthritis, Rheumatoid/virology; Disease Progression; Disease-Free Survival; Female; Humans; Immunoglobulin Heavy Chains/genetics; Immunohistochemistry; Lymphoproliferative Disorders/complications; Male; Middle Aged; Regression Analysis; Treatment Outcome; Virus Activation

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Full text: 1 Database: MEDLINE Main subject: Arthritis, Rheumatoid / Methotrexate / Herpesvirus 4, Human / Lymphoproliferative Disorders Type of study: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Year: 2013 Type: Article

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