Knockout of the tetraspanin Cd9 in the TRAMP model of de novo prostate cancer increases spontaneous metastases in an organ-specific manner.

Copeland, Ben T; Bowman, Matthew J; Boucheix, Claude; Ashman, Leonie K

Copeland, Ben T; Bowman, Matthew J; Boucheix, Claude; Ashman, Leonie K.

Affiliation

Copeland BT; School of Biomedical Sciences and Pharmacy, University of Newcastle and Cancer Research Program, Hunter Medical Research Institute, Newcastle, Australia.

Int J Cancer ; 133(8): 1803-12, 2013 Oct 15.

Article in En | MEDLINE | ID: mdl-23575960

Subject(s)

Adenocarcinoma/metabolism; Neoplasm Metastasis; Prostatic Neoplasms/metabolism; Prostatic Neoplasms/pathology; Tetraspanin 29/genetics; Adenocarcinoma/genetics; Adenocarcinoma/secondary; Animals; Apoptosis/genetics; Cell Adhesion; Cell Movement; Cell Proliferation; Disease Progression; Gene Knockout Techniques; Liver Neoplasms/secondary; Lung Neoplasms/secondary; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic/genetics; Prostatic Neoplasms/genetics

Key words

CD9; cancer; metastasis; prostate; tetraspanin

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Full text: 1 Database: MEDLINE Main subject: Prostatic Neoplasms / Adenocarcinoma / Tetraspanin 29 / Neoplasm Metastasis Limits: Animals Language: En Year: 2013 Type: Article

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