Diabetes-induced central neuritic dystrophy and cognitive deficits are associated with the formation of oligomeric reticulon-3 via oxidative stress.

Zhao, Bei; Pan, Bai-Shen; Shen, Su-Wen; Sun, Xiao; Hou, Zheng-Zhou; Yan, Riqiang; Sun, Feng-Yan

Zhao, Bei; Pan, Bai-Shen; Shen, Su-Wen; Sun, Xiao; Hou, Zheng-Zhou; Yan, Riqiang; Sun, Feng-Yan.

Affiliation

Zhao B; Institutes for Biomedical Science and Department of Neurobiology of the School of Basic Medical Sciences, Shanghai 200032.

J Biol Chem ; 288(22): 15590-9, 2013 May 31.

Article in En | MEDLINE | ID: mdl-23592790

Subject(s)

Carrier Proteins/metabolism; Cerebral Cortex/metabolism; Cognition Disorders/metabolism; Dementia/metabolism; Diabetes Mellitus, Experimental/metabolism; Diabetic Neuropathies/metabolism; Neurites/metabolism; Oxidative Stress; Protein Multimerization; Amyloid beta-Peptides/metabolism; Animals; Cell Line, Tumor; Cerebral Cortex/pathology; Cognition Disorders/pathology; Dementia/pathology; Diabetes Mellitus, Experimental/pathology; Diabetic Neuropathies/pathology; Hydrogen Peroxide/pharmacology; Male; Neurites/pathology; Oxidants/pharmacology; Protein Carbonylation/drug effects; Rats; Rats, Sprague-Dawley

Key words

Aggregation; Alzheimer Disease; Axon; Central Dystrophic Neurite; Dementia; Diabetes; Dystrophin; Oxidative Stress; Reticulon

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Full text: 1 Database: MEDLINE Main subject: Carrier Proteins / Cerebral Cortex / Neurites / Cognition Disorders / Oxidative Stress / Dementia / Diabetes Mellitus, Experimental / Diabetic Neuropathies / Protein Multimerization Type of study: Risk_factors_studies Limits: Animals Language: En Year: 2013 Type: Article

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