miR-150 blocks MLL-AF9-associated leukemia through oncogene repression.

Bousquet, Marina; Zhuang, Guoqing; Meng, Cong; Ying, Wei; Cheruku, Patali S; Shie, Andrew T; Wang, Stephanie; Ge, Guangtao; Wong, Piu; Wang, Gang; Safe, Stephen; Zhou, Beiyan

Bousquet, Marina; Zhuang, Guoqing; Meng, Cong; Ying, Wei; Cheruku, Patali S; Shie, Andrew T; Wang, Stephanie; Ge, Guangtao; Wong, Piu; Wang, Gang; Safe, Stephen; Zhou, Beiyan.

Affiliation

Bousquet M; Department of Physiology and Pharmacology, College of Veterinary Medicine, Texas A&M University, College Station, TX 77843, USA.

Mol Cancer Res ; 11(8): 912-22, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23604034

Subject(s)

Gene Expression Regulation, Leukemic; Leukemia/genetics; MicroRNAs/genetics; MicroRNAs/metabolism; Oncogene Proteins, Fusion/metabolism; Oncogenes; Animals; Apoptosis/genetics; Apoptosis/physiology; Cell Cycle/genetics; Cell Cycle/physiology; Early Growth Response Protein 2/genetics; Early Growth Response Protein 2/metabolism; Gene Expression Profiling; Genes, Tumor Suppressor; HEK293 Cells; Humans; Leukemia/metabolism; Leukemia/pathology; Mice; Mice, Inbred C57BL; Oncogene Proteins, Fusion/genetics; Proto-Oncogene Proteins c-cbl/genetics; Proto-Oncogene Proteins c-cbl/metabolism; Proto-Oncogene Proteins c-myb/genetics; Proto-Oncogene Proteins c-myb/metabolism; Signal Transduction; Xenograft Model Antitumor Assays

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Full text: 1 Database: MEDLINE Main subject: Oncogenes / Leukemia / Gene Expression Regulation, Leukemic / Oncogene Proteins, Fusion / MicroRNAs Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Year: 2013 Type: Article

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