Drosophila Proteins/metabolism; Drosophila melanogaster/enzymology; Membrane Proteins/metabolism; Methyltransferases/metabolism; Protein-Arginine N-Methyltransferases/metabolism; RNA-Binding Protein FUS/metabolism; RNA-Binding Protein FUS/toxicity; Repressor Proteins/metabolism; Adenosine/analogs & derivatives; Adenosine/pharmacology; Amyotrophic Lateral Sclerosis/genetics; Amyotrophic Lateral Sclerosis/pathology; Animals; Arginine/metabolism; Cytosol/metabolism; Disease Models, Animal; Drosophila Proteins/genetics; Drosophila melanogaster/drug effects; Drosophila melanogaster/genetics; Enzyme Inhibitors/pharmacology; Gene Deletion; Gene Knockdown Techniques; HEK293 Cells; Humans; Inclusion Bodies/drug effects; Inclusion Bodies/metabolism; Membrane Proteins/antagonists & inhibitors; Methylation/drug effects; Methyltransferases/genetics; Mutant Proteins/metabolism; Mutation/genetics; Protein Binding/drug effects; Protein Transport/drug effects; Protein-Arginine N-Methyltransferases/antagonists & inhibitors; Repressor Proteins/antagonists & inhibitors; Subcellular Fractions/drug effects; Subcellular Fractions/metabolism