In vivo tumor targeting of a recombinant single-chain antigen-binding protein.

Colcher, D; Bird, R; Roselli, M; Hardman, K D; Johnson, S; Pope, S; Dodd, S W; Pantoliano, M W; Milenic, D E; Schlom, J

Colcher, D; Bird, R; Roselli, M; Hardman, K D; Johnson, S; Pope, S; Dodd, S W; Pantoliano, M W; Milenic, D E; Schlom, J.

Affiliation

Colcher D; Laboratory of Tumor Immunology and Biology, National Cancer Institute, Bethesda, Md. 20892.

J Natl Cancer Inst ; 82(14): 1191-7, 1990 Jul 18.

Article in En | MEDLINE | ID: mdl-2362290

Subject(s)

Carcinoma/metabolism; Carrier Proteins/pharmacokinetics; Colonic Neoplasms/metabolism; Immunotoxins/pharmacokinetics; Amino Acid Sequence; Animals; Carrier Proteins/therapeutic use; Female; Half-Life; Humans; Immunoglobulin Fab Fragments/administration & dosage; Immunoglobulin Fab Fragments/pharmacokinetics; Immunotoxins/genetics; Immunotoxins/therapeutic use; Kidney/metabolism; Mice; Mice, Nude; Molecular Sequence Data; Recombinant Proteins/genetics; Recombinant Proteins/pharmacokinetics; Recombinant Proteins/therapeutic use; Tissue Distribution

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PubMed Links

Database: MEDLINE Main subject: Carcinoma / Carrier Proteins / Immunotoxins / Colonic Neoplasms Limits: Animals / Female / Humans Language: En Year: 1990 Type: Article

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Carcinoma / Carrier Proteins / Immunotoxins / Colonic Neoplasms Limits: Animals / Female / Humans Language: En Year: 1990 Type: Article