Cancer-associated missense mutations of caspase-8 activate nuclear factor-&#954;B signaling.

Ando, Mizuo; Kawazu, Masahito; Ueno, Toshihide; Fukumura, Kazutaka; Yamato, Azusa; Soda, Manabu; Yamashita, Yoshihiro; Choi, Young L; Yamasoba, Tatsuya; Mano, Hiroyuki

Cancer-associated missense mutations of caspase-8 activate nuclear factor-κB signaling.

Ando, Mizuo; Kawazu, Masahito; Ueno, Toshihide; Fukumura, Kazutaka; Yamato, Azusa; Soda, Manabu; Yamashita, Yoshihiro; Choi, Young L; Yamasoba, Tatsuya; Mano, Hiroyuki.

Affiliation

Ando M; Department of Medical Genomics, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

Cancer Sci ; 104(8): 1002-8, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23659359

Subject(s)

Carcinoma, Squamous Cell/genetics; Caspase 8/genetics; Head and Neck Neoplasms/genetics; Mutation, Missense; NF-kappa B/metabolism; Apoptosis/genetics; Carcinogenesis/genetics; Carcinogenesis/metabolism; Carcinoma, Squamous Cell/enzymology; Carcinoma, Squamous Cell/metabolism; Carcinoma, Squamous Cell/pathology; Caspase 8/metabolism; Cell Line, Tumor; HEK293 Cells; Head and Neck Neoplasms/enzymology; Head and Neck Neoplasms/metabolism; Head and Neck Neoplasms/pathology; Humans; Signal Transduction; Squamous Cell Carcinoma of Head and Neck

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Full text: 1 Database: MEDLINE Main subject: Carcinoma, Squamous Cell / NF-kappa B / Mutation, Missense / Caspase 8 / Head and Neck Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Year: 2013 Type: Article

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