Clearance of Pseudomonas aeruginosa foreign-body biofilm infections through reduction of the cyclic Di-GMP level in the bacteria.

Christensen, Louise D; van Gennip, Maria; Rybtke, Morten T; Wu, Hong; Chiang, Wen-Chi; Alhede, Morten; Høiby, Niels; Nielsen, Thomas E; Givskov, Michael; Tolker-Nielsen, Tim

Christensen, Louise D; van Gennip, Maria; Rybtke, Morten T; Wu, Hong; Chiang, Wen-Chi; Alhede, Morten; Høiby, Niels; Nielsen, Thomas E; Givskov, Michael; Tolker-Nielsen, Tim.

Affiliation

Christensen LD; Department of International Health, Immunology, and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Infect Immun ; 81(8): 2705-13, 2013 Aug.

Article in En | MEDLINE | ID: mdl-23690403

Subject(s)

Biofilms/growth & development; Cyclic GMP/analogs & derivatives; Pseudomonas aeruginosa/physiology; 3',5'-Cyclic-GMP Phosphodiesterases/genetics; 3',5'-Cyclic-GMP Phosphodiesterases/metabolism; Animals; Cyclic GMP/metabolism; Disease Models, Animal; Escherichia coli Proteins/genetics; Female; Mice; Mice, Inbred BALB C; Pseudomonas Infections/metabolism

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Full text: 1 Database: MEDLINE Main subject: Pseudomonas aeruginosa / Cyclic GMP / Biofilms Limits: Animals Language: En Year: 2013 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Pseudomonas aeruginosa / Cyclic GMP / Biofilms Limits: Animals Language: En Year: 2013 Type: Article