TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis.

Liu, Boyi; Escalera, Jasmine; Balakrishna, Shrilatha; Fan, Lu; Caceres, Ana I; Robinson, Eve; Sui, Aiwei; McKay, M Craig; McAlexander, M Allen; Herrick, Christina A; Jordt, Sven E

Liu, Boyi; Escalera, Jasmine; Balakrishna, Shrilatha; Fan, Lu; Caceres, Ana I; Robinson, Eve; Sui, Aiwei; McKay, M Craig; McAlexander, M Allen; Herrick, Christina A; Jordt, Sven E.

Affiliation

Liu B; Department of Pharmacology, Yale School of Medicine, 333 Cedar St., New Haven, CT 06510, USA.

FASEB J ; 27(9): 3549-63, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23722916

Subject(s)

Dermatitis, Allergic Contact/immunology; Dermatitis, Allergic Contact/metabolism; Inflammation/metabolism; Transient Receptor Potential Channels/metabolism; Animals; Dermatitis, Allergic Contact/drug therapy; Female; Inflammation/genetics; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazolone/toxicity; TRPA1 Cation Channel; Transient Receptor Potential Channels/antagonists & inhibitors; Transient Receptor Potential Channels/genetics

Key words

TRP channels; pruritis; sensory neurons

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Full text: 1 Database: MEDLINE Main subject: Dermatitis, Allergic Contact / Transient Receptor Potential Channels / Inflammation Limits: Animals Language: En Year: 2013 Type: Article

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