Pulmonary administration of PEGylated polylysine dendrimers: absorption from the lung versus retention within the lung is highly size-dependent.

Ryan, Gemma M; Kaminskas, Lisa M; Kelly, Brian D; Owen, David J; McIntosh, Michelle P; Porter, Christopher J H

Ryan, Gemma M; Kaminskas, Lisa M; Kelly, Brian D; Owen, David J; McIntosh, Michelle P; Porter, Christopher J H.

Affiliation

Ryan GM; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University , 381 Royal Pde, Parkville, Victoria, Australia, 3052.

Mol Pharm ; 10(8): 2986-95, 2013 Aug 05.

Article in En | MEDLINE | ID: mdl-23750747

Subject(s)

Dendrimers/chemistry; Dendrimers/pharmacokinetics; Lung/metabolism; Polyethylene Glycols/chemistry; Polylysine/chemistry; Absorption; Animals; Dendrimers/administration & dosage; Male; Rats; Rats, Sprague-Dawley

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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Polylysine / Dendrimers / Lung Limits: Animals Language: En Year: 2013 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Polyethylene Glycols / Polylysine / Dendrimers / Lung Limits: Animals Language: En Year: 2013 Type: Article