Extracellular wildtype and mutant SOD1 induces ER-Golgi pathology characteristic of amyotrophic lateral sclerosis in neuronal cells.

Sundaramoorthy, Vinod; Walker, Adam K; Yerbury, Justin; Soo, Kai Ying; Farg, Manal A; Hoang, Vy; Zeineddine, Rafaa; Spencer, Damian; Atkin, Julie D

Sundaramoorthy, Vinod; Walker, Adam K; Yerbury, Justin; Soo, Kai Ying; Farg, Manal A; Hoang, Vy; Zeineddine, Rafaa; Spencer, Damian; Atkin, Julie D.

Affiliation

Sundaramoorthy V; Department of Biochemistry, Latrobe Institute for Molecular Science, La Trobe University, Bundoora, Melbourne, VIC, 3086, Australia.

Cell Mol Life Sci ; 70(21): 4181-95, 2013 Nov.

Article in En | MEDLINE | ID: mdl-23765103

Subject(s)

Amyotrophic Lateral Sclerosis/metabolism; Endoplasmic Reticulum/metabolism; Golgi Apparatus/metabolism; Neurons/metabolism; Superoxide Dismutase/metabolism; Amyotrophic Lateral Sclerosis/genetics; Animals; Apoptosis; Cell Death; Cell Line; Humans; Immunohistochemistry; Mice; Motor Neurons/metabolism; Mutation; Protein Folding; Superoxide Dismutase/genetics; Superoxide Dismutase-1

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Full text: 1 Database: MEDLINE Main subject: Superoxide Dismutase / Endoplasmic Reticulum / Golgi Apparatus / Amyotrophic Lateral Sclerosis / Neurons Limits: Animals / Humans Language: En Year: 2013 Type: Article

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