Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.

Trevisan, Gabriela; Rossato, Mateus F; Hoffmeister, Carin; Oliveira, Sara M; Silva, Cássia R; Matheus, Filipe C; Mello, Gláucia C; Antunes, Edson; Prediger, Rui D S; Ferreira, Juliano

Trevisan, Gabriela; Rossato, Mateus F; Hoffmeister, Carin; Oliveira, Sara M; Silva, Cássia R; Matheus, Filipe C; Mello, Gláucia C; Antunes, Edson; Prediger, Rui D S; Ferreira, Juliano.

Affiliation

Trevisan G; Graduate Program in Biological Sciences, Toxicological Biochemistry, Department of Chemistry, Center of Natural and Exact Sciences, Federal University of Santa Maria, Santa Maria, RS 97105-900, Brazil.

Eur J Pharmacol ; 714(1-3): 332-44, 2013 Aug 15.

Article in En | MEDLINE | ID: mdl-23911956

Subject(s)

Nociception; Peritoneum/drug effects; TRPC Cation Channels/metabolism; TRPV Cation Channels/metabolism; Animals; Capsaicin/pharmacology; Gastrointestinal Transit/drug effects; Intestines/drug effects; Intestines/physiology; Isothiocyanates/pharmacology; Macrophages/cytology; Macrophages/drug effects; Male; Mast Cells/cytology; Mast Cells/drug effects; Nociception/drug effects; Peritoneum/immunology; Peritoneum/metabolism; Peritoneum/physiology; Rats; Rats, Wistar; Receptors, Neurokinin-1/metabolism; Substance P/pharmacology; TRPA1 Cation Channel; TRPC Cation Channels/agonists; TRPV Cation Channels/agonists

Key words

Allyl isothiocyanate; Capsaicin; Mast cells; Pain; Resiniferatoxin; Substance p

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Full text: 1 Database: MEDLINE Main subject: Peritoneum / TRPC Cation Channels / TRPV Cation Channels / Nociception Limits: Animals Language: En Year: 2013 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Peritoneum / TRPC Cation Channels / TRPV Cation Channels / Nociception Limits: Animals Language: En Year: 2013 Type: Article