CXCR4 prevents dispersion of granule neuron precursors in the adult dentate gyrus.

Schultheiß, Clara; Abe, Philipp; Hoffmann, Frauke; Mueller, Wiebke; Kreuder, Anna-Elisabeth; Schütz, Dagmar; Haege, Sammy; Redecker, Christoph; Keiner, Silke; Kannan, Suresh; Claasen, Jan-Hendrik; Pfrieger, Frank W; Stumm, Ralf

Schultheiß, Clara; Abe, Philipp; Hoffmann, Frauke; Mueller, Wiebke; Kreuder, Anna-Elisabeth; Schütz, Dagmar; Haege, Sammy; Redecker, Christoph; Keiner, Silke; Kannan, Suresh; Claasen, Jan-Hendrik; Pfrieger, Frank W; Stumm, Ralf.

Affiliation

Schultheiß C; Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.

Hippocampus ; 23(12): 1345-58, 2013 Dec.

Article in En | MEDLINE | ID: mdl-23929505

Subject(s)

Dentate Gyrus/cytology; Gene Expression Regulation, Developmental/physiology; Neurons/physiology; Receptors, CXCR4/metabolism; Age Factors; Animals; Anti-HIV Agents/pharmacology; Apolipoprotein A-I/genetics; Apolipoprotein A-I/metabolism; Benzylamines; Cell Differentiation/drug effects; Cells, Cultured; Chemokine CXCL12/pharmacology; Cyclams; Doublecortin Domain Proteins; Doublecortin Protein; Gene Expression Regulation, Developmental/genetics; Heterocyclic Compounds/pharmacology; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins/metabolism; Neural Stem Cells/drug effects; Neural Stem Cells/metabolism; Neurogenesis/drug effects; Neurons/drug effects; Neuropeptides/metabolism; Receptors, CXCR4/genetics; SOXB1 Transcription Factors/genetics; SOXB1 Transcription Factors/metabolism

Key words

CXCL12; migration; neurogenesis; stem cell; stromal cell-derived factor-1

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Gene Expression Regulation, Developmental / Dentate Gyrus / Receptors, CXCR4 / Neurons Limits: Animals Language: En Year: 2013 Type: Article

Fulltext

XML

PubMed Links

Search on Google