Autoinhibition and signaling by the switch II motif in the G-protein chaperone of a radical B12 enzyme.

Lofgren, Michael; Koutmos, Markos; Banerjee, Ruma

Lofgren, Michael; Koutmos, Markos; Banerjee, Ruma.

Affiliation

Lofgren M; From the Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48109-0600 and.

J Biol Chem ; 288(43): 30980-9, 2013 Oct 25.

Article in En | MEDLINE | ID: mdl-23996001

Subject(s)

Alkyl and Aryl Transferases/chemistry; Bacterial Proteins/chemistry; Guanosine Diphosphate/chemistry; Methylobacterium extorquens/enzymology; Molecular Chaperones/chemistry; Vitamin B 12/chemistry; Alkyl and Aryl Transferases/genetics; Alkyl and Aryl Transferases/metabolism; Amino Acid Motifs; Bacterial Proteins/genetics; Bacterial Proteins/metabolism; Crystallography, X-Ray; Guanosine Diphosphate/genetics; Guanosine Diphosphate/metabolism; Humans; Methylmalonyl-CoA Mutase/chemistry; Methylmalonyl-CoA Mutase/genetics; Methylmalonyl-CoA Mutase/metabolism; Methylobacterium extorquens/genetics; Molecular Chaperones/genetics; Molecular Chaperones/metabolism; Protein Structure, Quaternary; Protein Structure, Secondary; Vitamin B 12/genetics; Vitamin B 12/metabolism

Key words

Adenosylcobalamin; Crystal Structure; G-proteins; Signaling; Small GTPases

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Full text: 1 Database: MEDLINE Main subject: Bacterial Proteins / Vitamin B 12 / Molecular Chaperones / Alkyl and Aryl Transferases / Methylobacterium extorquens / Guanosine Diphosphate Limits: Humans Language: En Year: 2013 Type: Article

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