In vitro treatments of Echinococcus granulosus with fungal chitosan, as a novel biomolecule.
Asian Pac J Trop Biomed
; 3(10): 811-5, 2013 Oct.
Article
in En
| MEDLINE
| ID: mdl-24075347
ABSTRACT
OBJECTIVE:
To determined the antiparasitic activity of the isolated chitosan from Penicillium viridicatum, Penicillium aurantiogriseum and commercial chitosan against protoscolicidal of hydatid cysts were determined.METHODS:
After isolating chitosan from fungal cell walls, four concentrations (50, 100, 200, 400 µg/mL) of each type of prepared chitosan and commercial chitosan were used for 10, 30, 60, and 180 min, respectively.RESULTS:
Among different type of chitosan, commercial chitosan with the highest degree of deacetylation showed high scolicidal activity in vitro. Fungal chitosan could be recommended, as good as commercial chitosan, for hydatic cysts control.CONCLUSIONS:
It seems to be a good alternative to synthetic and chemical scolicidal.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Echinococcus granulosus
/
Chitosan
/
Fungi
/
Anthelmintics
Limits:
Animals
Language:
En
Year:
2013
Type:
Article