Cysteine promoted C-terminal hydrazinolysis of native peptides and proteins.

Adams, Anna L; Cowper, Ben; Morgan, Rachel E; Premdjee, Bhavesh; Caddick, Stephen; Macmillan, Derek

Adams, Anna L; Cowper, Ben; Morgan, Rachel E; Premdjee, Bhavesh; Caddick, Stephen; Macmillan, Derek.

Affiliation

Adams AL; Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ (United Kingdom).

Angew Chem Int Ed Engl ; 52(49): 13062-6, 2013 Dec 02.

Article in En | MEDLINE | ID: mdl-24123371

Subject(s)

Cysteine/chemistry; Hydrazines/chemistry; Peptides/chemistry; Proteins/chemistry; Amino Acid Sequence; Erythropoietin/chemistry; Glycopeptides/chemistry; Hepcidins/chemistry; Humans; Molecular Sequence Data; Ubiquitin/chemistry

Key words

acyl transfer; erythropoietin; hydrazides; native chemical ligation; peptides

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Full text: 1 Database: MEDLINE Main subject: Peptides / Proteins / Cysteine / Hydrazines Limits: Humans Language: En Year: 2013 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Peptides / Proteins / Cysteine / Hydrazines Limits: Humans Language: En Year: 2013 Type: Article