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Vascular delivery of rAAVrh74.MCK.GALGT2 to the gastrocnemius muscle of the rhesus macaque stimulates the expression of dystrophin and laminin α2 surrogates.
Chicoine, Louis G; Rodino-Klapac, Louise R; Shao, Guohong; Xu, Rui; Bremer, William G; Camboni, Marybeth; Golden, Bethannie; Montgomery, Chrystal L; Shontz, Kimberly; Heller, Kristin N; Griffin, Danielle A; Lewis, Sarah; Coley, Brian D; Walker, Christopher M; Clark, K Reed; Sahenk, Zarife; Mendell, Jerry R; Martin, Paul T.
Affiliation
  • Chicoine LG; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Rodino-Klapac LR; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Shao G; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Xu R; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Bremer WG; Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Camboni M; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Golden B; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Montgomery CL; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Shontz K; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Heller KN; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Griffin DA; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Lewis S; Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Coley BD; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Current address: Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
  • Walker CM; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Vaccines and Immunity, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Clark KR; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
  • Sahenk Z; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Department of Neurology, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [3] Centers for Gene Therapy, The Research Institute at Nationwide Children's
  • Mendell JR; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Department of Neurology, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [3] Centers for Gene Therapy, The Research Institute at Nationwide Children's
  • Martin PT; 1] Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, Ohio, USA [2] Centers for Gene Therapy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Mol Ther ; 22(4): 713-24, 2014 Apr.
Article in En | MEDLINE | ID: mdl-24145553
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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / Dystrophin / Laminin / Gene Transfer Techniques / Muscular Dystrophies Limits: Animals Language: En Year: 2014 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / Dystrophin / Laminin / Gene Transfer Techniques / Muscular Dystrophies Limits: Animals Language: En Year: 2014 Type: Article