Homogeneous expansion of human T-regulatory cells via tumor necrosis factor receptor 2.

Okubo, Yoshiaki; Mera, Toshiyuki; Wang, Limei; Faustman, Denise L

Okubo, Yoshiaki; Mera, Toshiyuki; Wang, Limei; Faustman, Denise L.

Affiliation

Okubo Y; Immunobiology Laboratory, Massachusetts General Hospital and Harvard Medical School, Rm 3602, MGH-East, Bldg 149, 13th Street, Boston, MA 02129.

Sci Rep ; 3: 3153, 2013 Nov 06.

Article in En | MEDLINE | ID: mdl-24193319

Subject(s)

Receptors, Tumor Necrosis Factor, Type II/metabolism; Animals; Antibodies, Monoclonal/immunology; CD4-Positive T-Lymphocytes/cytology; CD4-Positive T-Lymphocytes/drug effects; CD4-Positive T-Lymphocytes/metabolism; Cell Proliferation; Cells, Cultured; Cytokines/metabolism; Forkhead Transcription Factors/metabolism; Humans; Interleukin-2/genetics; Interleukin-2/metabolism; Interleukin-2/pharmacology; Receptors, Tumor Necrosis Factor, Type II/agonists; Receptors, Tumor Necrosis Factor, Type II/antagonists & inhibitors; Recombinant Proteins/biosynthesis; Recombinant Proteins/genetics; Recombinant Proteins/pharmacology; T-Lymphocytes, Regulatory/cytology; T-Lymphocytes, Regulatory/drug effects; T-Lymphocytes, Regulatory/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism; Tumor Necrosis Factor-alpha/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Receptors, Tumor Necrosis Factor, Type II Type of study: Guideline Limits: Animals / Humans Language: En Year: 2013 Type: Article

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