Activated macrophages promote hepatitis C virus entry in a tumor necrosis factor-dependent manner.

Fletcher, Nicola F; Sutaria, Rupesh; Jo, Juandy; Barnes, Amy; Blahova, Miroslava; Meredith, Luke W; Cosset, Francois-Loic; Curbishley, Stuart M; Adams, David H; Bertoletti, Antonio; McKeating, Jane A

Fletcher, Nicola F; Sutaria, Rupesh; Jo, Juandy; Barnes, Amy; Blahova, Miroslava; Meredith, Luke W; Cosset, Francois-Loic; Curbishley, Stuart M; Adams, David H; Bertoletti, Antonio; McKeating, Jane A.

Affiliation

Fletcher NF; Hepatitis C Research Group, Institute for Biomedical Research, University of Birmingham, Birmingham, UK.

Hepatology ; 59(4): 1320-30, 2014 Apr.

Article in En | MEDLINE | ID: mdl-24259385

Subject(s)

Carcinoma, Hepatocellular/virology; Hepacivirus/physiology; Liver Neoplasms/virology; Macrophage Activation/physiology; Macrophages/physiology; Tumor Necrosis Factor-alpha/physiology; Virus Internalization; Carcinoma, Hepatocellular/metabolism; Carcinoma, Hepatocellular/pathology; Cell Line, Tumor; Cell Polarity/physiology; Hep G2 Cells; Hepatitis C/metabolism; Hepatitis C/physiopathology; Humans; Immunity, Innate/physiology; Interleukin-1beta/physiology; Liver Neoplasms/metabolism; Liver Neoplasms/pathology; Occludin/metabolism; Tetraspanin 28/metabolism; Tight Junctions/physiology

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Full text: 1 Database: MEDLINE Main subject: Tumor Necrosis Factor-alpha / Hepacivirus / Carcinoma, Hepatocellular / Virus Internalization / Liver Neoplasms / Macrophage Activation / Macrophages Type of study: Prognostic_studies Limits: Humans Language: En Year: 2014 Type: Article

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