The bitter pill: clinical drugs that activate the human bitter taste receptor TAS2R14.

Levit, Anat; Nowak, Stefanie; Peters, Maximilian; Wiener, Ayana; Meyerhof, Wolfgang; Behrens, Maik; Niv, Masha Y

Levit, Anat; Nowak, Stefanie; Peters, Maximilian; Wiener, Ayana; Meyerhof, Wolfgang; Behrens, Maik; Niv, Masha Y.

Affiliation

Levit A; 2The Institute of Biochemistry, Food Science, and Nutrition, Robert H. Smith Faculty of Agriculture, Food, and Environment, The Hebrew University of Jerusalem, P.O. Box 12, Rehovot 76100, Israel. masha.niv@mail.huji.ac.il.

FASEB J ; 28(3): 1181-97, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24285091

Subject(s)

Receptors, G-Protein-Coupled/agonists; HEK293 Cells; Humans; Models, Biological; Structure-Activity Relationship

Key words

GPCRs; cross-reactivity; drug repositioning; multispecificity

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Full text: 1 Database: MEDLINE Main subject: Receptors, G-Protein-Coupled Type of study: Prognostic_studies Limits: Humans Language: En Year: 2014 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Receptors, G-Protein-Coupled Type of study: Prognostic_studies Limits: Humans Language: En Year: 2014 Type: Article