Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: a study by the Acute Leukemia French Association group.

Janin, Maxime; Mylonas, Elena; Saada, Véronique; Micol, Jean-Baptiste; Renneville, Aline; Quivoron, Cyril; Koscielny, Serge; Scourzic, Laurianne; Forget, Sébastien; Pautas, Cécile; Caillot, Denis; Preudhomme, Claude; Dombret, Hervé; Berthon, Céline; Barouki, Robert; Rabier, Daniel; Auger, Nathalie; Griscelli, Frank; Chachaty, Elisabeth; Leclercq, Edwige; Courtier, Marie-Hélène; Bennaceur-Griscelli, Annelise; Solary, Eric; Bernard, Olivier Adrien; Penard-Lacronique, Virginie; Ottolenghi, Chris; de Botton, Stéphane

Janin, Maxime; Mylonas, Elena; Saada, Véronique; Micol, Jean-Baptiste; Renneville, Aline; Quivoron, Cyril; Koscielny, Serge; Scourzic, Laurianne; Forget, Sébastien; Pautas, Cécile; Caillot, Denis; Preudhomme, Claude; Dombret, Hervé; Berthon, Céline; Barouki, Robert; Rabier, Daniel; Auger, Nathalie; Griscelli, Frank; Chachaty, Elisabeth; Leclercq, Edwige; Courtier, Marie-Hélène; Bennaceur-Griscelli, Annelise; Solary, Eric; Bernard, Olivier Adrien; Penard-Lacronique, Virginie; Ottolenghi, Chris; de Botton, Stéphane.

Affiliation

Janin M; Maxime Janin, Robert Barouki, Daniel Rabier, and Chris Ottolenghi, Biochimie Métabolique, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Necker-Enfants Malades; Maxime Janin, Robert Barouki, and Chris Ottolenghi, Institut National de la Santé et de la Recherche Médicale (INSERM) U747, Université Paris Descartes; Hervé Dombret, Hôpital Saint-Louis, Paris; Elena Mylonas, Cyril Quivoron, Laurianne Scourzic, Olivier Adrien Bernard, Virginie Penard-Lacronique, and Stéphane de Botton, INSER

J Clin Oncol ; 32(4): 297-305, 2014 Feb 01.

Article in En | MEDLINE | ID: mdl-24344214

Subject(s)

Biomarkers, Tumor/blood; Glutarates/blood; Isocitrate Dehydrogenase/genetics; Leukemia, Myeloid, Acute/blood; Leukemia, Myeloid, Acute/diagnosis; Mutation; Adult; Aged; Area Under Curve; Female; France; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute/genetics; Male; Mass Spectrometry; Middle Aged; Neoplasm, Residual/blood; Nuclear Proteins/blood; Nucleophosmin; Predictive Value of Tests; Prognosis; ROC Curve; Sensitivity and Specificity; Stereoisomerism; WT1 Proteins/blood

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Full text: 1 Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Biomarkers, Tumor / Glutarates / Isocitrate Dehydrogenase / Mutation Type of study: Clinical_trials / Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Year: 2014 Type: Article

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