Epiregulin is critical for the acinar cell regeneration of the submandibular gland in a mouse duct ligation model.

Nagai, Koichi; Arai, Hideo; Okudera, Michisato; Yamamura, Takashi; Oki, Hidero; Komiyama, Kazuo

Nagai, Koichi; Arai, Hideo; Okudera, Michisato; Yamamura, Takashi; Oki, Hidero; Komiyama, Kazuo.

Affiliation

Nagai K; Department of Pathology, Nihon University School of Dentistry, Tokyo, Japan.

J Oral Pathol Med ; 43(5): 378-87, 2014 May.

Article in En | MEDLINE | ID: mdl-24354788

Subject(s)

Acinar Cells/physiology; Epiregulin/analysis; Regeneration/physiology; Salivary Ducts/metabolism; Submandibular Gland Diseases/metabolism; Submandibular Gland/metabolism; Amphiregulin; Animals; Atrophy; Betacellulin/analysis; Cell Culture Techniques; Cell Proliferation/drug effects; Cells, Cultured; Disease Models, Animal; EGF Family of Proteins/analysis; Epidermal Growth Factor/analysis; Epidermal Growth Factor/drug effects; Epigen/analysis; Epiregulin/pharmacology; ErbB Receptors/analysis; ErbB Receptors/drug effects; Female; Heparin-binding EGF-like Growth Factor/analysis; Kallikreins/analysis; Kallikreins/drug effects; Ligation; Mice; Mice, Inbred C57BL; Peptidylprolyl Isomerase/analysis; Proliferating Cell Nuclear Antigen/analysis; Salivary Ducts/drug effects; Salivary Ducts/pathology; Submandibular Gland/pathology; Submandibular Gland Diseases/pathology; Transforming Growth Factor alpha/analysis; Transforming Growth Factor alpha/drug effects

Key words

acinar cell; duct obstruction; epiregulin; hyposalivation; mouse; submandibular gland

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Regeneration / Submandibular Gland / Submandibular Gland Diseases / Salivary Ducts / Acinar Cells / Epiregulin Type of study: Prognostic_studies Limits: Animals Language: En Year: 2014 Type: Article

Fulltext

XML

PubMed Links

Search on Google