Beneficial effects of resveratrol on respiratory chain defects in patients' fibroblasts involve estrogen receptor and estrogen-related receptor alpha signaling.

Lopes Costa, Alexandra; Le Bachelier, Carole; Mathieu, Lise; Rotig, Agnès; Boneh, Avihu; De Lonlay, Pascale; Tarnopolsky, Mark A; Thorburn, David R; Bastin, Jean; Djouadi, Fatima

Lopes Costa, Alexandra; Le Bachelier, Carole; Mathieu, Lise; Rotig, Agnès; Boneh, Avihu; De Lonlay, Pascale; Tarnopolsky, Mark A; Thorburn, David R; Bastin, Jean; Djouadi, Fatima.

Affiliation

Lopes Costa A; INSERM U747, Université Paris Descartes, Paris, France.

Hum Mol Genet ; 23(8): 2106-19, 2014 Apr 15.

Article in En | MEDLINE | ID: mdl-24365713

Subject(s)

Cytochrome-c Oxidase Deficiency/drug therapy; Electron Transport Complex IV/metabolism; Estrogen Receptor alpha/metabolism; Fibroblasts/drug effects; Receptors, Estrogen/metabolism; Skin/drug effects; Stilbenes/pharmacology; Anticarcinogenic Agents/pharmacology; Blotting, Western; Cells, Cultured; Cytochrome-c Oxidase Deficiency/metabolism; Cytochrome-c Oxidase Deficiency/pathology; Electron Transport/drug effects; Electron Transport Complex I/metabolism; Fibroblasts/metabolism; Fibroblasts/pathology; Humans; Lactates; Mitochondrial Membranes/metabolism; Oxygen Consumption/drug effects; Pyruvates; RNA, Small Interfering/genetics; Resveratrol; Signal Transduction/drug effects; Sirtuin 1/antagonists & inhibitors; Sirtuin 1/genetics; Sirtuin 1/metabolism; Skin/metabolism; Skin/pathology; ERRalpha Estrogen-Related Receptor

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Full text: 1 Database: MEDLINE Main subject: Skin / Stilbenes / Receptors, Estrogen / Electron Transport Complex IV / Cytochrome-c Oxidase Deficiency / Estrogen Receptor alpha / Fibroblasts Limits: Humans Language: En Year: 2014 Type: Article

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