ß-arrestin-1 drives endothelin-1-mediated podocyte activation and sustains renal injury.

Buelli, Simona; Rosanò, Laura; Gagliardini, Elena; Corna, Daniela; Longaretti, Lorena; Pezzotta, Anna; Perico, Luca; Conti, Sara; Rizzo, Paola; Novelli, Rubina; Morigi, Marina; Zoja, Carlamaria; Remuzzi, Giuseppe; Bagnato, Anna; Benigni, Ariela

Buelli, Simona; Rosanò, Laura; Gagliardini, Elena; Corna, Daniela; Longaretti, Lorena; Pezzotta, Anna; Perico, Luca; Conti, Sara; Rizzo, Paola; Novelli, Rubina; Morigi, Marina; Zoja, Carlamaria; Remuzzi, Giuseppe; Bagnato, Anna; Benigni, Ariela.

Affiliation

Buelli S; IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri," Centro Anna Maria Astori, Bergamo, Italy;

J Am Soc Nephrol ; 25(3): 523-33, 2014 Mar.

Article in En | MEDLINE | ID: mdl-24371298

Subject(s)

Arrestins/physiology; Endothelin-1/metabolism; Glomerulonephritis/chemically induced; Podocytes/physiology; Receptor, Endothelin A/metabolism; Animals; Cell Movement; Disease Models, Animal; Doxorubicin; ErbB Receptors/metabolism; Female; Glomerulonephritis/metabolism; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Snail Family Transcription Factors; Transcription Factors/metabolism; Transcriptional Activation; beta Catenin/metabolism; beta-Arrestin 1; beta-Arrestins; src-Family Kinases/metabolism

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Full text: 1 Database: MEDLINE Main subject: Endothelin-1 / Arrestins / Receptor, Endothelin A / Podocytes / Glomerulonephritis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Year: 2014 Type: Article

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