Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice.

Zhang, Xiaoyan; Huang, Shizheng; Gao, Min; Liu, Jia; Jia, Xiao; Han, Qifei; Zheng, Senfeng; Miao, Yifei; Li, Shuo; Weng, Haoyu; Xia, Xuan; Du, Shengnan; Wu, Wanfu; Gustafsson, Jan-Åke; Guan, Youfei

Zhang, Xiaoyan; Huang, Shizheng; Gao, Min; Liu, Jia; Jia, Xiao; Han, Qifei; Zheng, Senfeng; Miao, Yifei; Li, Shuo; Weng, Haoyu; Xia, Xuan; Du, Shengnan; Wu, Wanfu; Gustafsson, Jan-Åke; Guan, Youfei.

Affiliation

Zhang X; Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Cardiovascular Science of the Ministry of Education, Beijing 100191, China.

Proc Natl Acad Sci U S A ; 111(6): 2277-82, 2014 Feb 11.

Article in En | MEDLINE | ID: mdl-24464484

Subject(s)

Kidney Concentrating Ability/genetics; Receptors, Cytoplasmic and Nuclear/genetics; Animals; Aquaporin 2/genetics; Aquaporin 2/metabolism; Base Sequence; DNA Primers; Kidney/metabolism; Male; Mice; Mice, Knockout; Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear/metabolism

Key words

bile acid receptor; water homeostasis

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Receptors, Cytoplasmic and Nuclear / Kidney Concentrating Ability Limits: Animals Language: En Year: 2014 Type: Article

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Receptors, Cytoplasmic and Nuclear / Kidney Concentrating Ability Limits: Animals Language: En Year: 2014 Type: Article