Therapeutic modalities of squalenoyl nanocomposites in colon cancer: an ongoing search for improved efficacy.

Maksimenko, Andrei; Alami, Mouad; Zouhiri, Fatima; Brion, Jean-Daniel; Pruvost, Alain; Mougin, Julie; Hamze, Abdallah; Boissenot, Tanguy; Provot, Olivier; Desmaële, Didier; Couvreur, Patrick

Maksimenko, Andrei; Alami, Mouad; Zouhiri, Fatima; Brion, Jean-Daniel; Pruvost, Alain; Mougin, Julie; Hamze, Abdallah; Boissenot, Tanguy; Provot, Olivier; Desmaële, Didier; Couvreur, Patrick.

Affiliation

Maksimenko A; Faculté de Pharmacie, Université Paris-Sud , Institut Galien Paris Sud, UMR CNRS 8612, 5 rue J.-B. Clément, Châtenay-Malabry, Paris, F-92296, France.

ACS Nano ; 8(3): 2018-32, 2014 Mar 25.

Article in En | MEDLINE | ID: mdl-24555414

Subject(s)

Antineoplastic Agents/pharmacology; Antineoplastic Agents/therapeutic use; Colonic Neoplasms/drug therapy; Drug Design; Nanocomposites/administration & dosage; Nanocomposites/chemistry; Squalene/chemistry; Animals; Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacokinetics; Biological Transport; Cell Line, Tumor; Cell Proliferation/drug effects; Colonic Neoplasms/pathology; Deoxycytidine/analogs & derivatives; Deoxycytidine/chemistry; Deoxycytidine/pharmacokinetics; Deoxycytidine/pharmacology; Deoxycytidine/therapeutic use; Drug Carriers/administration & dosage; Drug Carriers/chemistry; Humans; Intracellular Space/metabolism; Mice; Nanocomposites/therapeutic use; Stilbenes/chemistry; Xenograft Model Antitumor Assays; Gemcitabine

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Full text: 1 Database: MEDLINE Main subject: Squalene / Drug Design / Colonic Neoplasms / Nanocomposites / Antineoplastic Agents Limits: Animals / Humans Language: En Year: 2014 Type: Article

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