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Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.
Rueedi, Rico; Ledda, Mirko; Nicholls, Andrew W; Salek, Reza M; Marques-Vidal, Pedro; Morya, Edgard; Sameshima, Koichi; Montoliu, Ivan; Da Silva, Laeticia; Collino, Sebastiano; Martin, François-Pierre; Rezzi, Serge; Steinbeck, Christoph; Waterworth, Dawn M; Waeber, Gérard; Vollenweider, Peter; Beckmann, Jacques S; Le Coutre, Johannes; Mooser, Vincent; Bergmann, Sven; Genick, Ulrich K; Kutalik, Zoltán.
Affiliation
  • Rueedi R; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland ; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Ledda M; Department of Food-Consumer Interaction, Nestlé Research Center, Lausanne, Switzerland.
  • Nicholls AW; Investigative Preclinical Toxicology, GlaxoSmithKline R&D, Ware, Herts, United Kingdom.
  • Salek RM; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom ; Department of Biochemistry & Cambridge Systems Biology Centre, University of Cambridge, Cambridge, United Kingdom.
  • Marques-Vidal P; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, Lausanne, Switzerland.
  • Morya E; Sensonomic Laboratory of Alberto Santos Dumont Research Support Association and IEP Sirio, Libanes Hospital, São Paulo, Brazil ; Edmond and Lily Safra International Institute of Neuroscience of Natal, Natal, Brazil.
  • Sameshima K; Department of Radiology and Oncology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
  • Montoliu I; Department of Bioanalytical Sciences, Nestlé Research Center, Lausanne, Switzerland.
  • Da Silva L; Department of Bioanalytical Sciences, Nestlé Research Center, Lausanne, Switzerland.
  • Collino S; Department of Bioanalytical Sciences, Nestlé Research Center, Lausanne, Switzerland.
  • Martin FP; Department of Bioanalytical Sciences, Nestlé Research Center, Lausanne, Switzerland.
  • Rezzi S; Department of Bioanalytical Sciences, Nestlé Research Center, Lausanne, Switzerland.
  • Steinbeck C; European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
  • Waterworth DM; Medical Genetics, GlaxoSmithKline, Philadelphia, Pennsylvania, United States of America.
  • Waeber G; Department of Medicine, Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
  • Vollenweider P; Department of Medicine, Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
  • Beckmann JS; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland ; Swiss Institute of Bioinformatics, Lausanne, Switzerland ; Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
  • Le Coutre J; Department of Food-Consumer Interaction, Nestlé Research Center, Lausanne, Switzerland ; Organization for Interdisciplinary Research Projects, The University of Tokyo, Yayoi, Bunkyo-ku, Tokyo, Japan.
  • Mooser V; Department of Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland.
  • Bergmann S; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland ; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Genick UK; Department of Food-Consumer Interaction, Nestlé Research Center, Lausanne, Switzerland.
  • Kutalik Z; Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland ; Swiss Institute of Bioinformatics, Lausanne, Switzerland ; Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, Lausanne, Switzerland.
PLoS Genet ; 10(2): e1004132, 2014 Feb.
Article in En | MEDLINE | ID: mdl-24586186
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Full text: 1 Database: MEDLINE Main subject: Urine / Polymorphism, Single Nucleotide / Metabolome / Metabolomics Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Year: 2014 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Urine / Polymorphism, Single Nucleotide / Metabolome / Metabolomics Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans / Male Language: En Year: 2014 Type: Article