Orexin/hypocretin role in reward: implications for opioid and other addictions.

Baimel, Corey; Bartlett, Selena E; Chiou, Lih-Chu; Lawrence, Andrew J; Muschamp, John W; Patkar, Omkar; Tung, Li-Wei; Borgland, Stephanie L

Baimel, Corey; Bartlett, Selena E; Chiou, Lih-Chu; Lawrence, Andrew J; Muschamp, John W; Patkar, Omkar; Tung, Li-Wei; Borgland, Stephanie L.

Affiliation

Baimel C; Department of Physiology and Pharmacology, The University of Calgary, Calgary, AB, Canada; Department of Anesthesiology, Pharmacology and Therapeutics, The University of British Columbia, Vancouver, BC, Canada.

Br J Pharmacol ; 172(2): 334-48, 2015 Jan.

Article in En | MEDLINE | ID: mdl-24641197

Subject(s)

Intracellular Signaling Peptides and Proteins/metabolism; Neuropeptides/metabolism; Reward; Substance-Related Disorders/metabolism; Animals; Dynorphins/metabolism; Ethanol/administration & dosage; Humans; Hypothalamus/metabolism; Orexin Receptors/metabolism; Orexins; Ventral Tegmental Area/metabolism

Key words

VTA; addiction; dopamine; dynorphin; hypocretin; morphine; orexin

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Full text: 1 Database: MEDLINE Main subject: Reward / Neuropeptides / Substance-Related Disorders / Intracellular Signaling Peptides and Proteins Limits: Animals / Humans Language: En Year: 2015 Type: Article

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