Proarrhythmic effects of aldosterone during myocardial ischemia-reperfusion: implication of the sarcolemmal-KATP channels.

Alexandre, Joachim; Puddu, Paolo-Emilio; Simard, Christophe; Hof, Thomas; Sallé, Laurent; Guinamard, Romain; Manrique, Alain; Rouet, René; Beygui, Farzin; Milliez, Paul

Alexandre, Joachim; Puddu, Paolo-Emilio; Simard, Christophe; Hof, Thomas; Sallé, Laurent; Guinamard, Romain; Manrique, Alain; Rouet, René; Beygui, Farzin; Milliez, Paul.

Affiliation

Alexandre J; *Department of Cardiology, CHU de Caen, Caen, France; Research Unit Signalisation, Électrophysiologie et Imagerie des Lésions d'Ischémie-Reperfusion Myocardique, Université de Caen Basse-Normandie, Caen, France; Department of Cardiovascular Sciences, Sapienza University, Rome, Italy; and §Université de Caen Basse-Normandie, Medical School, Caen, France.

J Cardiovasc Pharmacol ; 64(2): 134-41, 2014 Aug.

Article in En | MEDLINE | ID: mdl-24662493

Subject(s)

Aldosterone/metabolism; Heart Ventricles/metabolism; KATP Channels/metabolism; Sarcolemma/metabolism; Action Potentials/drug effects; Aldosterone/pharmacology; Animals; Benzopyrans/pharmacology; Dihydropyridines/pharmacology; Disease Models, Animal; Female; Glyburide/pharmacology; Heart Ventricles/drug effects; Heart Ventricles/physiopathology; In Vitro Techniques; KATP Channels/agonists; KATP Channels/antagonists & inhibitors; Male; Myocardial Reperfusion Injury/metabolism; Myocardial Reperfusion Injury/physiopathology; Perfusion; Rabbits

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Sarcolemma / Aldosterone / KATP Channels / Heart Ventricles Limits: Animals Language: En Year: 2014 Type: Article

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: Sarcolemma / Aldosterone / KATP Channels / Heart Ventricles Limits: Animals Language: En Year: 2014 Type: Article