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A Caenorhabditis elegans-based assay recognizes immunoglobulin light chains causing heart amyloidosis.
Diomede, Luisa; Rognoni, Paola; Lavatelli, Francesca; Romeo, Margherita; del Favero, Elena; Cantù, Laura; Ghibaudi, Elena; di Fonzo, Andrea; Corbelli, Alessandro; Fiordaliso, Fabio; Palladini, Giovanni; Valentini, Veronica; Perfetti, Vittorio; Salmona, Mario; Merlini, Giampaolo.
Affiliation
  • Diomede L; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy;
  • Rognoni P; Amyloid Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy;
  • Lavatelli F; Amyloid Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy;
  • Romeo M; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy;
  • del Favero E; Department of Medical Biotechnology and Translational Medicine University of Milan, Laboratorio Interdisciplinare Tecnologie Avanzate, Segrate, Italy;
  • Cantù L; Department of Medical Biotechnology and Translational Medicine University of Milan, Laboratorio Interdisciplinare Tecnologie Avanzate, Segrate, Italy;
  • Ghibaudi E; Department of Chemistry, University of Turin, Turin, Italy;
  • di Fonzo A; Amyloid Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy;
  • Corbelli A; Bio-imaging Unit, Department of Cardiovascular Research, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy; Renal Research Laboratory, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Cà Granda Ospedale Maggiore Policlin
  • Fiordaliso F; Bio-imaging Unit, Department of Cardiovascular Research, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy;
  • Palladini G; Amyloid Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Italy; and.
  • Valentini V; Amyloid Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy;
  • Perfetti V; Medical Oncology Unit, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.
  • Salmona M; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricovero e Cura a Carattere Scientifico-Istituto di Ricerche Farmacologiche "Mario Negri," Milan, Italy;
  • Merlini G; Amyloid Research and Treatment Center, Foundation Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Italy; and.
Blood ; 123(23): 3543-52, 2014 Jun 05.
Article in En | MEDLINE | ID: mdl-24665135
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin Light Chains / Caenorhabditis elegans / Heart Diseases / Amyloidosis Type of study: Prognostic_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Year: 2014 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin Light Chains / Caenorhabditis elegans / Heart Diseases / Amyloidosis Type of study: Prognostic_studies Limits: Adult / Aged / Animals / Female / Humans / Male / Middle aged Language: En Year: 2014 Type: Article